Radiotherapy for testicular cancer

Radiotherapy uses high-energy rays to destroy cancer cells. It is sometimes used to treat testicular seminomas and more rarely, non-seminomas.

What is radiotherapy?

Radiotherapy uses high-energy rays to destroy cancer cells, while doing as little harm as possible to normal cells nearby. It is sometimes used to treat testicular cancer. You may have radiotherapy to treat a seminoma and, more rarely, a non-seminoma.

If you have a stage 2 seminoma, you may have radiotherapy either:

  • instead of chemotherapy
  • or with chemotherapy.

Radiotherapy for stage 2 seminomas is given to reduce the small risk of the cancer returning in the lymph nodes at the back of the abdomen.

Having radiotherapy for testicular cancer

You normally have radiotherapy treatment in the hospital radiotherapy outpatient department as a series of short daily sessions. The treatments are usually given from Monday to Friday, with a rest at the weekend.

Each treatment takes 10 to 15 minutes. Your doctor will discuss the treatment and possible side effects with you. A course of radiotherapy for seminoma may last 2 to 3 weeks.

At the beginning of each session of radiotherapy, the radiographer will position you carefully on the couch and make sure you are comfortable.

During your treatment you will be alone in the room, but you can talk to the radiographer who will watch you from the next room. Radiotherapy is not painful, but you will have to lie still for a few minutes during the treatment.

Radiotherapy does not make you radioactive. It is safe for you to be with other people, including children, throughout your treatment.

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Planning your radiotherapy

Radiotherapy has to be carefully planned to make sure it’s as effective as possible. It’s planned by a cancer specialist (clinical oncologist) and it may take a few visits.

On your first visit to the radiotherapy department, you’ll be asked to have a CT scan or lie under a machine called a simulator, which takes x-rays of the area to be treated.

You may need some small marks made on your skin to help the radiographer (who gives you your treatment) position you accurately and to show where the rays will be aimed at. These marks need to be able to be seen throughout your treatment, so permanent marks (like tiny tattoos) are usually used. These are extremely small, and will only be done with your permission. It may be a little uncomfortable while they are done.

Side effects

Radiotherapy to your tummy (abdomen) can cause side effects. But these can usually be controlled with medicines. Your doctor or specialist nurse will tell you more about what to expect. These side effects usually disappear gradually once your course of treatment has finished.

It is important to let your doctor know if you are having any problems with side effects. Most side effects are mild, and you can have medicines to treat them successfully.

Skin changes

The skin in the treated area may become red (if you have white skin) or darker (if you have black or brown skin). But this will improve after your treatment finishes. You will get advice on looking after your skin. Your specialist can prescribe cream if your skin is sore or uncomfortable.

Feeling sick nausea

Radiotherapy to the tummy area may make you feel sick. Your doctor will prescribe anti-sickness medicine to prevent or stop this. They will probably advise you to take these medicines regularly during treatment. Let your doctor know if the tablets are not working for you. There are other medicines they can prescribe.


Radiotherapy often makes people feel tired, especially towards the end of treatment. Try to pace yourself, and avoid doing anything that you do not really need to do. Gentle exercise, such as short walks, can help to improve tiredness. It is good to balance this with plenty of rest.

Sometimes, tiredness can last up to 8 weeks or longer after treatment finishes. Your energy levels will then slowly improve.


You might get some diarrhoea, but you can usually control this with medicines your doctor can prescribe. Let your doctor know if this is a problem. Make sure you drink plenty of fluids. Try to eat fewer high-fibre foods, such as fruit, vegetables, beans, pulses and wholewheat cereals.

Effects on fertility

Radiotherapy to the lymph nodes in the tummy will not affect your ability to have sex. It does not usually cause infertility. But your specialist may advise you to think about storing sperm before treatment starts.

Preventing pregnancy

During radiotherapy, a small dose of radiation reaches the remaining testicle. This may temporarily affect your sperm. So you will be advised to use effective contraception during treatment.

There is no evidence that radiotherapy has any effect on children you have after treatment. But you are usually advised to use contraception for 6 to 12 months after treatment. This allows time for your sperm to recover from any damage that treatment may have caused.

About our information

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    This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been reviewed by expert medical and health professionals and people living with cancer. It has been approved by Senior Medical Editor, Dr Jim Barber, Consultant Clinical Oncologist.

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