Knowing the extent of the lymphoma helps your doctor plan the right treatment. This is called staging.
Your doctor will also ask you about any symptoms you have. All this information helps doctors plan the right treatment for you.
Staging of lymphoma can sometimes be complicated. Your doctor or specialist nurse will explain what stage you have.
The stage of a lymphoma is usually described using numbers from 1 to 4. Stages 1 and 2 are sometimes called early stage (limited or localised lymphoma). Stages 3 and 4 are sometimes called advanced lymphoma. In some situations, stage 2 lymphoma that is large (bulky – see below) is treated as advanced disease.
The lymphoma is either:
- in a single lymph node, one group of lymph nodes, or in one organ of the lymphatic system, such as the tonsils
- or in another part of the body outside the lymph system (extra-nodal – see below).
Stage 2The lymphoma is either:
- in two or more groups of lymph nodes
- or in another part of the body (extra-nodal) and in one group of lymph nodes.
There are areas of lymphoma above and below the diaphragm.
There are areas of lymphoma outside and separate from the lymphatic system. For example, this could be in organs such as the bone marrow, lungs or liver.
Stage 4 – Lymphoma has also spread to the lung and bone marrow
Lymphoma is sometimes found in parts of the body outside the lymph nodes. This is called extra-nodal lymphoma. Extra-nodal sites include the liver, lungs, spinal cord and bone marrow.
Extra-nodal lymphoma is described by adding the letter E (for extra-nodal) after the stage number. For example, the lymphoma may be described as 1E.
If you have extra-nodal lymphoma, your doctor can explain to you how this affects the stage.
This term is used to describe:
- an area of HL that is 10cm (4 inches) or more in diameter
- a tumour in the centre of your chest (mediastinum) that is at least a third of the width of your chest.
The letter X may be added after the stage number. For example, the lymphoma may be described as 1X.
Sometimes the letter B is added after the stage number. For example, the lymphoma may be described as stage 1B. This is used to show if you have any symptoms that doctors call B symptoms. The B symptoms are:
- heavy drenching night sweats
- unexplained high temperatures
- unexplained weight loss.
If you have any B symptoms, it usually means the lymphoma is more advanced. If you do not have any of these symptoms, the letter A is used instead, for example stage 1A.
Below is a sample of the sources used in our Hodgkin lymphoma (HL) information. If you would like more information about the sources we use, please contact us at email@example.comHodgkin lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up; European Society for Medical Oncology (2018).
National Institute of Health and Care Excellence (NICE). Blood and bone marrow cancers. NICE Pathways. Last accessed 3 December 2020.
This information has been written, revised and edited by Macmillan Cancer Support’s Cancer Information Development team. It has been reviewed by expert medical and health professionals and people living with cancer. It has been approved by Senior Medical Editor, Professor Rajnish Gupta, Macmillan Consultant Medical Oncologist.
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